Homo sapiens glutamate ionotropic receptor NMDA type subunit 2A (GRIN2 - Nucleotide

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METTL14-mediated m6A epitranscriptomic modification contributes to chemotherapy-induced neuropathic pain by stabilizing GluN2A expression via IGF2BP2. [J Clin Invest. 2024]
METTL14-mediated m6A epitranscriptomic modification contributes to chemotherapy-induced neuropathic pain by stabilizing GluN2A expression via IGF2BP2.
Lu W, Yang X, Zhong W, Chen G, Guo X, Ye Q, Xu Y, Qi Z, Ye Y, Zhang J, et al. J Clin Invest. 2024 Feb 6; 134(6). Epub 2024 Feb 6.
Differential functional consequences of GRIN2A mutations associated with schizophrenia and neurodevelopmental disorders. [Sci Rep. 2024]
Differential functional consequences of GRIN2A mutations associated with schizophrenia and neurodevelopmental disorders.
Shepard N, Baez-Nieto D, Iqbal S, Kurganov E, Budnik N, Campbell AJ, Pan JQ, Sheng M, Farsi Z. Sci Rep. 2024 Feb 2; 14(1):2798. Epub 2024 Feb 2.
Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids. [Cell Mol Life Sci. 2024]
Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids.
Kysilov B, Kuchtiak V, Hrcka Krausova B, Balik A, Korinek M, Fili K, Dobrovolski M, Abramova V, Chodounska H, Kudova E, et al. Cell Mol Life Sci. 2024 Jan 12; 81(1):36. Epub 2024 Jan 12.

RefSeq alternative splicing
See 11 reference mRNA sequence splice variants for the GRIN2A gene.
RefSeq protein product
See the reference protein sequence for glutamate receptor ionotropic, NMDA 2A isoform 1 precursor (NP_000824.1).

Protein
Protein sequence from Nucleotide coding region
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GluN2A [Guide to Pharmacology]
GluN2A
Guide to Pharmacology
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Nucleotide