Homo sapiens mutL homolog 1 (MLH1), transcript variant 1, mRNA

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Pick Primers
Design and test primers for this sequence using Primer-BLAST.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Unmasking early colorectal cancer clues: in silico and in vitro investigation of downregulated IGF2, SOCS1, MLH1, and CACNA1G in SSA polyps. [Mol Biol Rep. 2024]
Unmasking early colorectal cancer clues: in silico and in vitro investigation of downregulated IGF2, SOCS1, MLH1, and CACNA1G in SSA polyps.
Mirbahari SN, Fatemi N, Savabkar S, Chaleshi V, Zali N, Taleghani MY, Mirzaei E, Rejali L, Moghadam PK, Mojarad EN. Mol Biol Rep. 2024 Jun 14; 51(1):764. Epub 2024 Jun 14.
TDP43 interacts with MLH1 and MSH6 proteins in a DNA damage-inducible manner. [Mol Brain. 2024]
TDP43 interacts with MLH1 and MSH6 proteins in a DNA damage-inducible manner.
Provasek VE, Kodavati M, Kim B, Mitra J, Hegde ML. Mol Brain. 2024 Jun 5; 17(1):32. Epub 2024 Jun 5.
Histone H3K9 Lactylation Confers Temozolomide Resistance in Glioblastoma via LUC7L2-Mediated MLH1 Intron Retention. [Adv Sci (Weinh). 2024]
Histone H3K9 Lactylation Confers Temozolomide Resistance in Glioblastoma via LUC7L2-Mediated MLH1 Intron Retention.
Yue Q, Wang Z, Shen Y, Lan Y, Zhong X, Luo X, Yang T, Zhang M, Zuo B, Zeng T, et al. Adv Sci (Weinh). 2024 May; 11(19):e2309290. Epub 2024 Mar 13.

RefSeq alternative splicing
See 33 reference mRNA sequence splice variants for the MLH1 gene.
RefSeq protein product
See the reference protein sequence for DNA mismatch repair protein Mlh1 isoform 1 (NP_000240.1).

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
Taxonomy sequences associated with Nucleotide record
Annotated Genomic
Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
BioSystems
BioSystems
CCDS
Link to Consensus CDS
Components (Core)
Links to Core components
Full text in PMC
Free full text articles in PMC
Functional Class
Functional class of the sequence domain architecture
Gene
Link to related Genes
OMIM
OMIM records associated with Nucleotide sequence
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed

Dryad Digital Repository [Dryad Digital Repository]
Dryad Digital Repository
GenScript latest version of gene cDNA ORF Clone [GenScript latest version of g...]
GenScript latest version of gene cDNA ORF Clone
Order TALEN/CRISPR clone [GeneCopoeia Inc.]
Order TALEN/CRISPR clone
GeneCopoeia Inc.
Order qPCR primer [GeneCopoeia Inc.]
Order qPCR primer
GeneCopoeia Inc.
Order full-length cDNA clone [GeneCopoeia Inc.]
Order full-length cDNA clone
GeneCopoeia Inc.
UCSC Genome Browser [UCSC Genome Browser]
UCSC Genome Browser