Homo sapiens class II major histocompatibility complex transactivator - Nucleotide

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The intrinsically disordered transcriptional activation domain of CIITA is functionally tuneable by single substitutions: An exception or a new paradigm? [Protein Sci. 2024]
The intrinsically disordered transcriptional activation domain of CIITA is functionally tuneable by single substitutions: An exception or a new paradigm?
Sreenivasan S, Heffren P, Suh KS, Rodnin MV, Kosa E, Fenton AW, Ladokhin AS, Smith PE, Fontes JD, Swint-Kruse L. Protein Sci. 2024 Feb; 33(2):e4863.
The NLR member CIITA: Master controller of adaptive and intrinsic immunity and unexpected tool in cancer immunotherapy. [Biomed J. 2023]
The NLR member CIITA: Master controller of adaptive and intrinsic immunity and unexpected tool in cancer immunotherapy.
Forlani G, Shallak M, Gatta A, Shaik AKB, Accolla RS. Biomed J. 2023 Oct; 46(5):100631. Epub 2023 Jul 17.
NLRC5-CIITA Fusion Protein as an Effective Inducer of MHC-I Expression and Antitumor Immunity. [Int J Mol Sci. 2023]
NLRC5-CIITA Fusion Protein as an Effective Inducer of MHC-I Expression and Antitumor Immunity.
Santharam MA, Shukla A, Levesque D, Kufer TA, Boisvert FM, Ramanathan S, Ilangumaran S. Int J Mol Sci. 2023 Apr 13; 24(8). Epub 2023 Apr 13.

RefSeq alternative splicing
See 48 reference mRNA sequence splice variants for the CIITA gene.
RefSeq protein product
See the reference protein sequence for MHC class II transactivator isoform 2 (NP_000237.2).

Protein
Protein sequence from Nucleotide coding region
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Homologene neighbors for GEO Profiles (Select 111052234) (0)
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Chromosome neighbors for GEO Profiles (Select 111076620) (20)
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Chromosome neighbors for GEO Profiles (Select 111051554) (20)
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Chromosome neighbors for GEO Profiles (Select 111051573) (20)
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Chromosome neighbors for GEO Profiles (Select 111055354) (18)
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Nucleotide