Homo sapiens dihydropyrimidine dehydrogenase (DPYD), transcript varian - Nucleotide

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Lethal Capecitabine Toxicity in Patients With Complete Dihydropyrimidine Dehydrogenase Deficiency Due to Ultra-Rare DPYD Variants. [JCO Precis Oncol. 2024]
Lethal Capecitabine Toxicity in Patients With Complete Dihydropyrimidine Dehydrogenase Deficiency Due to Ultra-Rare DPYD Variants.
van Kuilenburg ABP, Pleunis-van Empel MCH, Brouwer RB, Sijben AEJ, Knapen DG, Oude Munnink TH, van Zanden JJ, Janssens-Puister J, Dobritzsch D, Meinsma R, et al. JCO Precis Oncol. 2024 May; 8:e2300599.
Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD). [Elife. 2024]
Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD).
Zhang T, Ambrodji A, Huang H, Bouchonville KJ, Etheridge AS, Schmidt RE, Bembenek BM, Temesgen ZB, Wang Z, Innocenti F, et al. Elife. 2024 Apr 30; 13. Epub 2024 Apr 30.
MIR27A rs895819 TC genotype increases risk of fluoropyrimidine-induced severe toxicity independently of DPYD variations. [Pharmacogenomics. 2024]
MIR27A rs895819 TC genotype increases risk of fluoropyrimidine-induced severe toxicity independently of DPYD variations.
Ragia G, Biziota E, Koukaki T, Amarantidis K, Manolopoulos VG. Pharmacogenomics. 2024 Jan; 25(2):59-67. Epub 2024 Feb 14.

RefSeq alternative splicing
See 11 reference mRNA sequence splice variants for the DPYD gene.
RefSeq protein product
See the reference protein sequence for dihydropyrimidine dehydrogenase (NP_000101.2).

Protein
Protein sequence from Nucleotide coding region
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dihydropyrimidine dehydrogenase [Guide to Pharmacology]
dihydropyrimidine dehydrogenase
Guide to Pharmacology
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sushi domain-containing protein 1 isoform 2 precursor [Homo sapiens]
sushi domain-containing protein 1 isoform 2 precursor [Homo sapiens]
gi|42476320|ref|NP_071931.2|

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Nucleotide