Homo sapiens F-box and leucine rich repeat protein 4 (FBXL4), RefSeqGe - Nucleotide

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Excessive BNIP3- and BNIP3L-dependent mitophagy underlies the pathogenesis of FBXL4-mutated mitochondrial DNA depletion syndrome. [Autophagy. 2024]
Excessive BNIP3- and BNIP3L-dependent mitophagy underlies the pathogenesis of FBXL4-mutated mitochondrial DNA depletion syndrome.
Gao K, Chen Y, Mo R, Wang C. Autophagy. 2024 Feb; 20(2):460-462. Epub 2024 Jan 25.
FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors. [EMBO J. 2023]
FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors.
Nguyen-Dien GT, Kozul KL, Cui Y, Townsend B, Kulkarni PG, Ooi SS, Marzio A, Carrodus N, Zuryn S, Pagano M, et al. EMBO J. 2023 Jul 3; 42(13):e112767. Epub 2023 May 10.
FBXL4 ubiquitin ligase deficiency promotes mitophagy by elevating NIX levels. [EMBO J. 2023]
FBXL4 ubiquitin ligase deficiency promotes mitophagy by elevating NIX levels.
Elcocks H, Brazel AJ, McCarron KR, Kaulich M, Husnjak K, Mortiboys H, Clague MJ, Urbé S. EMBO J. 2023 Jul 3; 42(13):e112799. Epub 2023 Apr 27.