Homo sapiens DNA polymerase epsilon, catalytic subunit (POLE), RefSeqG - Nucleotide

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The P286R mutation of DNA polymerase ε activates cancer-cell-intrinsic immunity and suppresses endometrial tumorigenesis via the cGAS-STING pathway. [Cell Death Dis. 2024]
The P286R mutation of DNA polymerase ε activates cancer-cell-intrinsic immunity and suppresses endometrial tumorigenesis via the cGAS-STING pathway.
Tang M, Yin S, Zeng H, Huang A, Huang Y, Hu Z, Shah AR, Zhang S, Li H, Chen G. Cell Death Dis. 2024 Jan 18; 15(1):69. Epub 2024 Jan 18.
Race, Prevalence of POLE and POLD1 Alterations, and Survival Among Patients With Endometrial Cancer. [JAMA Netw Open. 2024]
Race, Prevalence of POLE and POLD1 Alterations, and Survival Among Patients With Endometrial Cancer.
Zheng S, Donnelly ED, Strauss JB. JAMA Netw Open. 2024 Jan 2; 7(1):e2351906. Epub 2024 Jan 2.
Cervical Cytology Preserves Histologically Detected Surface Epithelial Slackening, Unique to the POLE Mutation-subtype in Endometrial Cancer. [In Vivo. 2024]
Cervical Cytology Preserves Histologically Detected Surface Epithelial Slackening, Unique to the POLE Mutation-subtype in Endometrial Cancer.
Kitazono I, Akahane T, Yokoyama S, Kubota E, Nishida-Kirita Y, Noguchi H, Murakami M, Yanazume S, Kobayashi H, Tanimoto A. In Vivo. 2024 Jan-Feb; 38(1):321-333.

RefSeq alternative splicing
See 11 reference mRNA sequence splice variants for the POLE gene.

Protein
Protein sequence from Nucleotide coding region
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sensor histidine kinase [Listeria seeligeri serovar 1/2b str. SLCC3954]
sensor histidine kinase [Listeria seeligeri serovar 1/2b str. SLCC3954]
gi|289434077|ref|YP_003463949.1|

Protein

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Nucleotide