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Homo sapiens full open reading frame cDNA clone RZPDo834H1220D for gene FEN1, flap structure-specific endonuclease 1; complete cds, incl. stopcodon

GenBank: CR536562.1

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Articles about the FEN1 gene

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons. [Neuron. 2024]
MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.
Liu Y, Flamier A, Bell GW, Diao AJ, Whitfield TW, Wang HC, Wu Y, Schulte F, Friesen M, Guo R, et al. Neuron. 2024 Jun 19; 112(12):1943-1958.e10. Epub 2024 May 1.
The endonuclease FEN1 mediates activation of STAT3 and facilitates proliferation and metastasis in breast cancer. [Mol Biol Rep. 2024]
The endonuclease FEN1 mediates activation of STAT3 and facilitates proliferation and metastasis in breast cancer.
Wu M, Huang X, Wu B, Zhu M, Zhu Y, Yu L, Lan T, Liu J. Mol Biol Rep. 2024 Apr 20; 51(1):553. Epub 2024 Apr 20.
FEN1 Inhibition as a Potential Novel Targeted Therapy against Breast Cancer and the Prognostic Relevance of FEN1. [Int J Mol Sci. 2024]
FEN1 Inhibition as a Potential Novel Targeted Therapy against Breast Cancer and the Prognostic Relevance of FEN1.
Berfelde J, Hildebrand LS, Kuhlmann L, Fietkau R, Distel LV. Int J Mol Sci. 2024 Feb 9; 25(4). Epub 2024 Feb 9.

Reference sequence information

RefSeq mRNA
See reference mRNA sequence for the FEN1 gene (NM_004111.6).

More about the FEN1 gene

The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand...
Also Known As: FEN-1, MF1, RAD2

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