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Homo sapiens cDNA, FLJ79279 complete cds, highly similar to DNA topoisomerase I, mitochondrial precursor(EC 5.99.1.2)

GenBank: AK316380.1

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Articles about the TOP1MT gene

Association of TOP1MT with immune infiltration and checkpoint in colorectal cance. [Asian J Surg. 2024]
Association of TOP1MT with immune infiltration and checkpoint in colorectal cance.
Wang H, Yan W, Yu Z. Asian J Surg. 2024 Feb; 47(2):1042-1044. Epub 2023 Nov 2.
Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT. [Hum Mol Genet. 2023]
Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT.
Al Khatib I, Deng J, Lei Y, Torres-Odio S, Rojas GR, Newman LE, Chung BK, Symes A, Zhang H, Huang SN, et al. Hum Mol Genet. 2023 Jul 20; 32(15):2422-2440.
TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1. [J Cell Biol. 2023]
TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.
Zhou J, Rasmussen NL, Olsvik HL, Akimov V, Hu Z, Evjen G, Kaeser-Pebernard S, Sankar DS, Roubaty C, Verlhac P, et al. J Cell Biol. 2023 Feb 6; 222(2). Epub 2022 Dec 27.

Reference sequence information

RefSeq alternative splicing
See 34 reference mRNA sequence splice variants for the TOP1MT gene.

More about the TOP1MT gene

This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB ...

Related information

Protein
Protein sequence from Nucleotide coding region
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Taxonomy sequences associated with Nucleotide record
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reagents [ExactAntigen/Labome]
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ExactAntigen/Labome

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Pseudomonas chlororaphis strain January_TSA5D8 16S ribosomal RNA gene, partial s...
Pseudomonas chlororaphis strain January_TSA5D8 16S ribosomal RNA gene, partial sequence
gi|482514931|gb|KC776520.1|

Nucleotide
Homologene neighbors for GEO Profiles (Select 77982582) (0)
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BioAssays, RNAi Target, Active for Gene (Select 4490) (1)
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