Homo sapiens lymphoid enhancer binding factor 1 (LEF1), RefSeqGene on - Nucleotide

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Downregulation of TCF7 and LEF1 is a key determinant of tumor-infiltrating regulatory T-cell function. [Int Immunol. 2024]
Downregulation of TCF7 and LEF1 is a key determinant of tumor-infiltrating regulatory T-cell function.
Kidani Y, Kitagawa Y, Hagiwara M, Kawashima A, Kanazawa T, Wada H, Uemura M, Nonomura N, Motooka D, Nakamura S, et al. Int Immunol. 2024 Mar 9; 36(4):167-182.
A distinct isoform of lymphoid enhancer binding factor 1 (LEF1) epigenetically restricts EBV reactivation to maintain viral latency. [PLoS Pathog. 2023]
A distinct isoform of lymphoid enhancer binding factor 1 (LEF1) epigenetically restricts EBV reactivation to maintain viral latency.
Ward BJH, Prasai K, Schaal DL, Wang J, Scott RS. PLoS Pathog. 2023 Dec; 19(12):e1011873. Epub 2023 Dec 19.
LEF1 isoforms regulate cellular senescence and aging. [Aging Cell. 2023]
LEF1 isoforms regulate cellular senescence and aging.
Jia M, Sayed K, Kapetanaki MG, Dion W, Rosas L, Irfan S, Valenzi E, Mora AL, Lafyatis RA, Rojas M, et al. Aging Cell. 2023 Dec; 22(12):e14024. Epub 2023 Nov 13.

RefSeq alternative splicing
See 12 reference mRNA sequence splice variants for the LEF1 gene.

Protein
Protein sequence from Nucleotide coding region
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RNA
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SNP
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Zapoteca caracasana AND 1[s_discriminator] (0)
dbGaP
LEF1[gene] (43)
ClinVar
lymphoid enhancer-binding factor 1 isoform X1 [Homo sapiens]
lymphoid enhancer-binding factor 1 isoform X1 [Homo sapiens]
gi|2462597471|ref|XP_054206128.1|

Protein
PREDICTED: Homo sapiens lymphoid enhancer binding factor 1 (LEF1), transcript va...
PREDICTED: Homo sapiens lymphoid enhancer binding factor 1 (LEF1), transcript variant X1, mRNA
gi|2217350861|ref|XM_005263046.4|

Nucleotide
Tssr30398 AND (alive[prop]) (0)
Gene

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Nucleotide