Toll-Like Receptor 7 - MeSH

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Items: 5

Select item 680511991.

A pattern recognition receptor that binds several forms of imidazo-quinoline including the antiviral compound Imiquimod.

Year introduced: 2006(2005)

Select item 675230972.

N-(4-(4-amino-2-ethyl-1H-imidazo(4,5c)quinolin-1-yl)butyl)methanesulfonamide [Supplementary Concept]

structure in first source

Date introduced: September 27, 2007

Select item 674953483.

TLR7 protein, human [Supplementary Concept]

RefSeq NM_016562

Date introduced: July 29, 2005

Select item 674896394.

TLR7 protein, rat [Supplementary Concept]

RefSeq XM_228909

Date introduced: September 10, 2004

Select item 674770385.

Tlr7 protein, mouse [Supplementary Concept]

Results suggest novel signaling pathway in murine macrophages involving synergy between toll-like receptors 2, 4, 7, and 9 and adenosine A(2A)receptors, that up-regulates VEGF and down-regulates TNFalpha expression, thus acting as an angiogenic switch; RefSeq NM_133211

Date introduced: September 9, 2003

MeSH

NLM Controlled Vocabulary

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