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Spike Glycoprotein, Coronavirus

A class I viral fusion protein that forms the characteristic spikes, or peplomers, found on the viral surface that mediate virus attachment, fusion, and entry into the host cell. During virus maturation, it is cleaved into two subunits: S1, which binds to receptors in the host cell, and S2, which mediates membrane fusion.

Year introduced: 2014

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Subheadings:

Tree Number(s): D12.776.543.512.500.665, D12.776.964.970.880.910.665

MeSH Unique ID: D064370

Entry Terms:

  • Coronavirus Spike Glycoprotein
  • Glycoprotein S, Coronavirus
  • Spike Glycoproteins, Coronavirus
  • Spike Protein, Coronavirus
  • Coronavirus Spike Protein
  • Spike Glycoprotein, Bovine Coronavirus
  • Spike Protein S2, Coronavirus
  • E2 Spike Glycoprotein, Coronavirus
  • Spike Glycoprotein S1, Coronavirus

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