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Acid Phosphatase
An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.
Year introduced: /blood was BLOOD ACID PHOSPHATASE 1963-1967
Tartrate-Resistant Acid Phosphatase
One of several acid phosphatases in humans, other mammals, plants, and a few prokaryotes. The protein fold of tartrate-resistant acid phosphatase (TRAP) resembles that of the catalytic domain of plant purple acid phosphatase and other serine/threonine-protein phosphatases that also contain a metallophosphoesterase domain. One gene produces the various forms which include purple acid phosphatases from spleen and other tissues. Tartrate-resistant acid phosphatase is a biomarker for pathological states in which it is over-expressed. Such conditions include GAUCHER DISEASE; HODGKIN DISEASE; BONE RESORPTION; and NEOPLASM METASTASIS.
Year introduced: 2017 (1995)
prostatic acid phosphatase [Supplementary Concept]
Date introduced: June 14, 2001
purple acid phosphatase [Supplementary Concept]
110-kDa glycoprotein with Fe(III)-Zn(II) center; isolated from the red kidney bean Phaseolus vulgaris; GenBank P80366 (PAP1) and (PAP2); RefSeq NM_122874 (PAP26)
Date introduced: January 23, 1995
Acp4 protein, rat [Supplementary Concept]
RefSeq NM_001107510
Date introduced: October 13, 2004
PLPP4 protein, human [Supplementary Concept]
RefSeq NM_001030059
Date introduced: November 1, 2007
ACP2 protein, human [Supplementary Concept]
RefSeq NM_001610
Date introduced: August 8, 2007
ACP6 protein, human [Supplementary Concept]
high expression in human intestinal tissues; RefSeq NM_016361
Date introduced: July 9, 2002
Acp6 protein, mouse [Supplementary Concept]
RefSeq NM_019800
phosphatidic acid phosphatase type 2 [Supplementary Concept]
amino acid sequence in first source; GenBank AF123611
Date introduced: April 7, 2000
lipid phosphate phosphatase [Supplementary Concept]
a Mg2+-independent phosphatidate phosphatase from S cerevisiae; RefSeq NM_022538 (rat); NM_008247 (mouse); NM_176895 (human)
Date introduced: July 9, 1998
ACP4 protein, human [Supplementary Concept]
RefSeq NM_033068
Date introduced: May 17, 2017
ACP5 protein, human [Supplementary Concept]
RefSeq:NM_001111034
Date introduced: October 26, 2016
Phosphatidate Phosphatase
A phosphomonoesterase involved in the synthesis of triacylglycerols. It catalyzes the hydrolysis of phosphatidates with the formation of diacylglycerols and orthophosphate. EC 3.1.3.4.
Year introduced: 1991(1979)
Acid Phosphatase Deficiency [Supplementary Concept]
Date introduced: November 5, 2012
prostatic acid phosphatase (248-286), human [Supplementary Concept]
forms amyloid fibrils, call SEVI (semen-derived enhancer of virus infection), that trap HIV virions and enhance infectivity
Date introduced: February 11, 2008
PLPP5 protein, human [Supplementary Concept]
RefSeq NM_001102559
Acp2 protein, rat [Supplementary Concept]
RefSeq NM_016988
Acp2 protein, mouse [Supplementary Concept]
RefSeq NM_007387
PPIP5K1 protein, human [Supplementary Concept]
RefSeq NM_014659
Date introduced: May 13, 2007