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senkirkine [Supplementary Concept]
macrocyclic secopyrrolizidine alkaloid from Senecio; structure given in first source; RN given refers to senkirkine
Date introduced: January 1, 1975
Pyrrolizidine Alkaloids
A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS.
Year introduced: 1973(1971)
Heterocyclic Compounds, 2-Ring
A class of heterocyclic compounds that include a two-ring fused structure. Both aromatic and non-aromatic ring structures are included in this category.
Year introduced: 1998
Heterocyclic Compounds
Cyclic compounds that include atoms other than carbon in their ring structure.
Alkaloids
Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable kingdoms, and some have been synthesized. (Grant and Hackh's Chemical Dictionary, 5th ed)
Heterocyclic Compounds, Fused-Ring
Multiple ring heterocyclic compounds containing two or more rings that share two atoms and one bond in common.
Year introduced: 2017