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5-Methoxypsoralen
A linear furanocoumarin that has phototoxic and anti-inflammatory properties, with effects similar to METHOXSALEN. It is used in PUVA THERAPY for the treatment of PSORIASIS.
Year introduced: 2019 (1980)
Photosensitizing Agents
Drugs that are pharmacologically inactive but when exposed to ultraviolet radiation or sunlight are converted to their active metabolite to produce a beneficial reaction affecting the diseased tissue. These compounds can be administered topically or systemically and have been used therapeutically to treat psoriasis and various types of neoplasms.
Year introduced: 1993
Dermatologic Agents
Drugs used to treat or prevent skin disorders or for the routine care of skin.
Year introduced: 1967
Anti-Inflammatory Agents
Substances that reduce or suppress INFLAMMATION.
Year introduced: 1966(1964)
Pyrans
Furocoumarins
Polycyclic compounds consisting of a furan ring fused with coumarin. They commonly occur in PLANTS, especially UMBELLIFERAE and RUTACEAE, as well as PSORALEA.
Year introduced: 2015 (1979)
Heterocyclic Compounds, 3-Ring
A class of heterocyclic compounds that include a three-ring fused structure. Both aromatic or non-aromatic ring structures are included in this category.
Year introduced: 1998
Heterocyclic Compounds, 2-Ring
A class of heterocyclic compounds that include a two-ring fused structure. Both aromatic and non-aromatic ring structures are included in this category.
Heterocyclic Compounds, 1-Ring
Organic compounds that contain a ring structure made up of carbon and one or more additional elements such as nitrogen and oxygen.
Heterocyclic Compounds
Cyclic compounds that include atoms other than carbon in their ring structure.
Coumarins
Synthetic or naturally occurring substances related to coumarin, the delta-lactone of coumarinic acid.
Benzopyrans
Compounds with a core of fused benzo-pyran rings.
Year introduced: 1966
Heterocyclic Compounds, Fused-Ring
Multiple ring heterocyclic compounds containing two or more rings that share two atoms and one bond in common.
Year introduced: 2017
Therapeutic Uses
Uses of chemicals which affect the course of conditions, diseases, syndromes or pathology to benefit the health of an individual.
Year introduced: 2004
Pharmacologic Actions
A broad category of chemical actions and uses that result in the prevention, treatment, cure or diagnosis of disease. Included here are drugs and chemicals that act by altering normal body functions, such as the REPRODUCTIVE CONTROL AGENTS and ANESTHETICS. Effects of chemicals on the environment are also included.
Year introduced: 2004(1999)
Chemical Actions and Uses
A group of pharmacologic activities, effects on living systems and the environment, and modes of employment of drugs and chemicals. They are broken into actions, which describe their effects, and uses, which describe how they are employed.
Year introduced: 1999
Radiation-Sensitizing Agents
Drugs used to potentiate the effectiveness of radiation therapy in destroying unwanted cells.
Year introduced: 1966(1965)