Epidermal Nevus [Supplementary Concept]
Congenital lesions that affect about 1 in 1,000 people and appear at or shortly after birth as localized epidermal thickening with hyperpigmentation that frequently follow the lines of Blaschko (normally invisible lines of cell development in the skin that follow a "V" shape over the back, "S" shaped whirls over the chest, and sides, and wavy shapes on the head.). They can result from post-zygotic, somatic mutations in the KRAS, HRAS, NRAS, FGFR3, or PIK3CA genes. OMIM: 162900
Date introduced: October 24, 2013
MeSH Unique ID: C580062
Heading Mapped to:
Entry Terms:
- Nevus, Epidermal
- Epidermal Naevus
- Nevus, Keratinocytic, Nonepidermolytic