Centrifugation, Isopycnic

A technique used to separate particles according to their densities in a continuous density gradient. The sample is usually mixed with a solution of known gradient materials and subjected to centrifugation. Each particle sediments to the position at which the gradient density is equal to its own. The range of the density gradient is usually greater than that of the sample particles. It is used in purifying biological materials such as proteins, nucleic acids, organelles, and cell types.

Year introduced: 1991(1975)

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Tree Number(s): E05.181.724.336.253, E05.196.941.336.253

MeSH Unique ID: D002500

Entry Terms:

• Isopycnic Centrifugation

All MeSH Categories
Analytical, Diagnostic and Therapeutic Techniques and Equipment Category
Investigative Techniques
Centrifugation
Ultracentrifugation
Centrifugation, Density Gradient
Centrifugation, Isopycnic

All MeSH Categories
Analytical, Diagnostic and Therapeutic Techniques and Equipment Category
Investigative Techniques
Chemistry Techniques, Analytical
Ultracentrifugation
Centrifugation, Density Gradient
Centrifugation, Isopycnic