Integrin beta Chains

Integrin beta chains combine with integrin alpha chains to form heterodimeric cell surface receptors. Integrins have traditionally been classified into functional groups based on the identity of one of three beta chains present in the heterodimer. The beta chain is necessary and sufficient for integrin-dependent signaling. Its short cytoplasmic tail contains sequences critical for inside-out signaling.

Year introduced: 2003

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Tree Number(s): D12.776.543.750.705.408.200

MeSH Unique ID: D039641

Entry Terms:

• beta Chains, Integrin
• beta Integrins
• Integrins, beta
• Integrin beta Subunits

Previous Indexing:

• Integrins (1990-2002)

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Membrane Proteins
Receptors, Cell Surface
Receptors, Immunologic
Integrins
Integrin beta Chains
CD18 Antigens
Integrin beta1
Integrin beta3
Integrin beta4