Amino Acid Chloromethyl Ketones

Inhibitors of SERINE ENDOPEPTIDASES and sulfhydryl group-containing enzymes. They act as alkylating agents and are known to interfere in the translation process.

Year introduced: 1977

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Tree Number(s): D12.125.065

MeSH Unique ID: D000590

Entry Terms:

• Peptide Chloromethyl Ketones
• Chloromethyl Ketones, Peptide
• Ketones, Peptide Chloromethyl

Previous Indexing:

• Peptides (1966-1976)
• specific amino acid (1966-1976)

Pharmacologic Action:

• Alkylating Agents
• Protein Synthesis Inhibitors
• Serine Proteinase Inhibitors

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Amino Acids
Amino Acid Chloromethyl Ketones
Tosyllysine Chloromethyl Ketone
Tosylphenylalanyl Chloromethyl Ketone