Gene Fusion

The GENETIC RECOMBINATION of the parts of two or more GENES resulting in a gene with different or additional regulatory regions, or a new chimeric gene product. ONCOGENE FUSION includes an ONCOGENE as at least one of the fusion partners and such gene fusions are often detected in neoplastic cells and are transcribed into ONCOGENE FUSION PROTEINS. ARTIFICIAL GENE FUSION is carried out in vitro by RECOMBINANT DNA technology.

Year introduced: 2006

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Tree Number(s): G05.728.385

MeSH Unique ID: D050939

Entry Terms:

• Fusion, Gene
• Fusions, Gene
• Gene Fusions

Previous Indexing:

• Artificial Gene Fusion (1998-2005)

See Also:

• Artificial Gene Fusion
• Mutant Chimeric Proteins

All MeSH Categories
Phenomena and Processes Category
Genetic Phenomena
Recombination, Genetic
Gene Fusion
Oncogene Fusion