Retinaldehyde
A diterpene derived from the carotenoid VITAMIN A which functions as the active component of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation straightens-out the bend of the retinal molecule and causes a change in the shape of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed reactions convert the 11-trans-retinal back to the cis-isomer.
Year introduced: 1991(1975)
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Subheadings:
Tree Number(s): D02.047.850, D02.455.326.271.665.202.495.690, D02.455.426.392.368.367.379.249.700.690, D02.455.849.131.495.690, D02.455.849.291.605, D23.767.261.700.690
MeSH Unique ID: D012172
Registry Number: RR725D715M
Entry Terms:
- Retinene
- Retinyl Aldehydde
- Aldehydde, Retinyl
- Axerophthal
- Retinal
- 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-Nonatetraenal
- Vitamin A Aldehyde
- Aldehyde, Vitamin A
- 11-cis-Retinal
- 11 cis Retinal
- 11-trans-Retinal
- 11 trans Retinal
- all-trans-Retinal
- all trans Retinal