Polyendocrinopathies, Autoimmune
Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (CANDIDIASIS, CHRONIC MUCOCUTANEOUS), while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE), lymphocytic thyroiditis (THYROIDITIS, AUTOIMMUNE;), HYPOPARATHYROIDISM; and gonadal failure. In both types organ-specific ANTIBODIES against a variety of ENDOCRINE GLANDS have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.
Year introduced: 1992
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Subheadings:
Tree Number(s): C19.787, C20.111.750
MeSH Unique ID: D016884
Entry Terms:
- Autoimmune Polyendocrinopathy
- Polyendocrinopathy, Autoimmune
- Polyglandular Type I Autoimmune Syndrome
- AIRE Deficiency
- AIRE Deficiencies
- Deficiency, AIRE
- APECED
- APS Type 1
- Autoimmune Polyendocrinopathy Syndrome Type 1
- Autoimmune Polyendocrinopathy with Candidiasis and Ectodermal Dystrophy
- Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy
- Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy
- Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy, Autoimmune
- Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy
- Autoimmune Polyglandular Syndrome Type I
- Autoimmune Polyglandular Syndrome, Type 1
- Autoimmune Polyglandular Syndrome, Type I
- Autoimmune Syndrome Type I, Polyglandular
- Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy, Autoimmune
- Polyendocrinopathy Candidiasis Ectodermal Dystrophy, Autoimmune
- Polyglandular Autoimmune Syndrome, Type 1
- Polyglandular Autoimmune Syndrome, Type I
- Polyglandular Type II Autoimmune Syndrome
- Autoimmune Polyendocrine Syndrome, Type 2
- Autoimmune Polyendocrine Syndrome, Type II
- Autoimmune Polyglandular Syndrome Type II
- Autoimmune Syndrome Type II, Polyglandular
- Diabetes Mellitus, Addison Disease, Myxedema
- Diabetes Mellitus, Addison's Disease, Myxedema
- Multiple Endocrine Deficiency Syndrome, Type 2
- Polyendocrine Autoimmune Syndrome, Type II
- Polyglandular Autoimmune Syndrome, Type 2
- Polyglandular Deficiency Syndrome, Type 2
- Schmidt Syndrome
- Syndrome, Schmidt
- Schmidt's Syndrome
- Syndrome, Schmidt's
- Polyglandular Type III Autoimmune Syndrome
- Autoimmune Polyglandular Syndrome Type III
- Autoimmune Polyglandular Syndrome, Type 3
- Autoimmune Syndrome Type III, Polyglandular
- Polyglandular Autoimmune Syndrome, Type 3
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