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Sea-Blue Histiocyte Syndrome

A congenital disease caused by an inborn error involving APOLIPOPROTEINS E leading to abnormal LIPID METABOLISM and the accumulation of GLYCOSPHINGOLIPIDS, particularly SPHINGOMYELINS in the HISTIOCYTES. This disorder is characterized by SPLENOMEGALY and the sea-blue histiocytes in the spleen and bone marrow after May Grunwald staining.

Year introduced: 1984

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Tree Number(s): C10.228.140.163.100.435.825.775, C15.604.250.410.800, C16.320.565.189.435.825.775, C16.320.565.398.641.803.850, C16.320.565.595.554.825.775, C18.452.132.100.435.825.775, C18.452.584.563.641.803.850, C18.452.648.189.435.825.775, C18.452.648.398.641.803.850, C18.452.648.595.554.825.775

MeSH Unique ID: D012618

Entry Terms:

  • Histiocyte Syndrome, Sea-Blue
  • Histiocyte Syndromes, Sea-Blue
  • Sea Blue Histiocyte Syndrome
  • Sea-Blue Histiocyte Syndromes
  • Syndrome, Sea-Blue Histiocyte
  • Syndromes, Sea-Blue Histiocyte
  • Histiocytosis, Sea-Blue
  • Histiocytoses, Sea-Blue
  • Histiocytosis, Sea Blue
  • Sea-Blue Histiocytoses
  • Histiocyte Syndrome, Sea Blue
  • Sea Blue Histiocytosis
  • Histiocytoses, Sea Blue
  • Sea Blue Histiocytoses
  • Sea-Blue Histiocyte Disease
  • Disease, Sea-Blue Histiocyte
  • Diseases, Sea-Blue Histiocyte
  • Histiocyte Disease, Sea-Blue
  • Histiocyte Diseases, Sea-Blue
  • Sea Blue Histiocyte Disease
  • Sea-Blue Histiocyte Diseases
  • Sea-Blue Histiocytosis
  • Histiocyte Syndromes, Sea Blue

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