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Synaptic Transmission

The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.

Year introduced: 1994

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Subheadings:

Tree Number(s): G02.111.820.850, G04.835.850, G07.265.880, G11.561.830

MeSH Unique ID: D009435

Entry Terms:

  • Transmission, Neural
  • Neural Transmission
  • Transmission, Synaptic
  • Neurotransmission

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