Arterial calcification of infancy [Supplementary Concept]

A severe hereditary autosomal recessive disorder characterized by calcification of the internal elastic lamina of muscular arteries and STENOSIS due to myointimal proliferation. It is often fatal within the first 6 months of life because of MYOCARDIAL ISCHEMIA resulting in refractory HEART FAILURE. Mutations in the ENPP1 gene have been identified. OMIM: 208000

Date introduced: August 25, 2010

MeSH Unique ID: C537440

Heading Mapped to:

• Vascular Calcification

Entry Terms:

• Occlusive infantile arteriopathy
• Idiopathic infantile arterial calcification
• Generalized arterial calcification in infancy
• Arterial Calcification, Generalized, Of Infancy
• Arteriopathy, Occlusive Infantile
• GACI
• Arterial Calcification, Idiopathic Infantile