teplizumab [Supplementary Concept]

a humanized anti-CD3 monoclonal antibody that has been mutated to reduce Fc receptor and complement binding, used in treatment of type I diabetes

Date introduced: August 3, 2005

MeSH Unique ID: C502540

Registry Number: S4M959U2IJ

Heading Mapped to:

• Antibodies, Monoclonal, Humanized

Entry Terms:

• OKT3gamma1 Ala-Ala, humanized
• hOKT3gamma1(Ala-Ala)
• humanized OKT3 gamma1(Ala-Ala)
• humanized OKT3gamma1(Ala-Ala)
• MGA-031
• MGA031

Previous Indexing:

• MUROMONAB-CD3 (2005-2011)