poly (A)-binding protein I - MeSH

Search results

Items: 1 to 20 of 23

<< First< Prev

Page of 2

Select item 680391031.

A poly(A) binding protein that is involved in promoting the extension of the poly A tails of MRNA. The protein requires a minimum of ten ADENOSINE nucleotides in order for binding to mRNA. Once bound it works in conjunction with CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR to stimulate the rate of poly A synthesis by POLY A POLYMERASE. Once poly-A tails reach around 250 nucleotides in length poly(A) binding protein II no longer stimulates POLYADENYLATION. Mutations within a GCG repeat region in the gene for poly(A) binding protein II have been shown to cause the disease MUSCULAR DYSTROPHY, OCULOPHARYNGEAL.

Year introduced: 2003

Select item 680391222.

Poly(A)-Binding Protein I

A poly(A) binding protein that has a variety of functions such as mRNA stabilization and protection of RNA from nuclease activity. Although poly(A) binding protein I is considered a major cytoplasmic RNA-binding protein it is also found in the CELL NUCLEUS and may be involved in transport of mRNP particles.

Year introduced: 2003

Select item 680391023.

Poly(A)-Binding Proteins

Proteins that bind to the 3' polyadenylated region of MRNA. When complexed with RNA the proteins serve an array of functions such as stabilizing the 3' end of RNA, promoting poly(A) synthesis and stimulating mRNA translation.

Year introduced: 2003

Select item 674105954.

poly-U binding splicing factor 60KDa [Supplementary Concept]

FBP (FUSE-binding protein)-interacting repressor (FIR) targets TFIIH to inhibit activated transcription; amino acid sequence in first source

Date introduced: July 14, 2000

Select item 675019035.

PCBP2 protein, human [Supplementary Concept]

RefSeq NM_005016

Date introduced: September 16, 2005

Select item 675311896.

PABPN1L protein, human [Supplementary Concept]

RefSeq NM_001080487