Scleromyxedema

A connective tissue disorder characterized by widespread thickening of SKIN with a cobblestone-like appearance. It is caused by proliferation of FIBROBLASTS and deposition of MUCIN in the DERMIS in the absence of thyroid disease. Most scleromyxedema cases are associated with a MONOCLONAL GAMMOPATHY, immunoglobulin IgG-lambda.

Year introduced: 2007

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Tree Number(s): C17.300.550.875

MeSH Unique ID: D053718

Entry Terms:

• Papular Mucinosis
• Mucinosis, Papular
• Lichen Myxedematosus
• Myxedematosus, Lichen

Previous Indexing:

• Myxedema (1963-2006)

See Also:

• Myxedema

All MeSH Categories
Diseases Category
Skin and Connective Tissue Diseases
Connective Tissue Diseases
Mucinoses
Scleromyxedema