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caspase-activated deoxyribonuclease [Supplementary Concept]
degrades DNA during apoptosis, inhibited by ICAD (inhibitor of CAD); a protein of 343 amino acids carrying a nuclear localization signal; amino acid sequence in first source
Date introduced: January 14, 1998
caspase-activated DNase inhibitor [Supplementary Concept]
from mouse T-lymphoma, with two forms short (S) & long (L); ICAD is the mouse homolog of human DFF45
Dffb protein, rat [Supplementary Concept]
triggers DNA fragmentation and chromatin condensation during apoptosis; RefSeq NM_053362
Date introduced: November 2, 2004
DFFB protein, human [Supplementary Concept]
triggers DNA fragmentation and chromatin condensation during apoptosis; RefSeq NM_001004285
Date introduced: August 18, 1998