antifungals - MeSH

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Select item 680009351.

Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.

Year introduced: 1967

Select item 820009352.

Antifungal Agents [Pharmacological Action]

Select item 680588883.

14-alpha Demethylase Inhibitors

Compounds that specifically inhibit STEROL 14-DEMETHYLASE. A variety of azole-derived ANTIFUNGAL AGENTS act through this mechanism.

Year introduced: 2011

Select item 680251414.

Drug Resistance, Fungal

The ability of fungi to resist or to become tolerant to chemotherapeutic agents, antifungal agents, or antibiotics. This resistance may be acquired through gene mutation.

Year introduced: 2002

Select item 680150385.

Zineb

An agricultural fungicide of the dithiocarbamate class. It has relatively low toxicity and there is little evidence of human injury from exposure.

Year introduced: 1991(1972)

Select item 680143346.

Tropolone

A seven-membered aromatic ring compound. It is structurally related to a number of naturally occurring antifungal compounds (ANTIFUNGAL AGENTS).

Year introduced: 1991(1975)

Select item 680140477.

Tolnaftate

A synthetic antifungal agent.

Year introduced: 1973(1972)

Select item 680124588.

Salicylanilides

2-Hydroxy-N-phenylbenzamides. N-phenyl substituted salicylamides. Derivatives have been used as fungicides, anti-mildew agents and topical antifungal agents. In concentrated form may cause irritation of skin and mucous membranes.

Year introduced: 1991(1977)

Select item 680091819.

Mycoses

Diseases caused by FUNGI.

Select item 6800876710.

Methylmercury Compounds

Organic compounds in which mercury is attached to a methyl group.

Year introduced: 1980

Select item 6800834411.

Maneb

Manganese derivative of ethylenebisdithiocarbamate. It is used in agriculture as a fungicide and has been shown to cause irritation to the eyes, nose, skin, and throat.

Year introduced: 1991(1972)

Select item 6800565912.

Fungicides, Industrial

Chemicals that kill or inhibit the growth of fungi in agricultural applications, on wood, plastics, or other materials, in swimming pools, etc.

Year introduced: 1972

Select item 6800565813.

Fungi

A kingdom of eukaryotic, heterotrophic organisms that live parasitically as saprobes, including MUSHROOMS; YEASTS; smuts, molds, etc. They reproduce either sexually or asexually, and have life cycles that range from simple to complex. Filamentous fungi, commonly known as molds, refer to those that grow as multicellular colonies.

Select item 6800543714.

Flucytosine

A fluorinated cytosine analog that is used as an antifungal agent.

Year introduced: 1987(1972)

Select item 6800503515.

Ethylmercury Compounds

Organic mercury compounds in which the mercury is attached to an ethyl group.

Year introduced: 1980

Select item 6800503416.

Ethylmercuric Chloride

A highly toxic compound used as a fungicide for treating seeds.

Year introduced: 1991(1980)