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Items: 12

1.

Anti-Anxiety Agents

Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here.

Year introduced: 1995

3.

Zolazepam

A pyrazolodiazepinone with pharmacological actions similar to ANTI-ANXIETY AGENTS. It is commonly used in combination with TILETAMINE to obtain immobilization and anesthesia in animals.

Year introduced: 1991(1977)

4.

Tranquilizing Agents

A traditional grouping of drugs said to have a soothing or calming effect on mood, thought, or behavior. Included here are the ANTI-ANXIETY AGENTS (minor tranquilizers), ANTIMANIC AGENTS, and the ANTIPSYCHOTIC AGENTS (major tranquilizers). These drugs act by different mechanisms and are used for different therapeutic purposes.

5.

Psychotropic Drugs

A loosely defined grouping of drugs that have effects on psychological function. Here the psychotropic agents include the antidepressive agents, hallucinogens, and tranquilizing agents (including the antipsychotics and anti-anxiety agents).

Year introduced: 1975

6.

Premedication

Preliminary administration of a drug preceding a diagnostic, therapeutic, or surgical procedure. The commonest types of premedication are antibiotics (ANTIBIOTIC PROPHYLAXIS) and anti-anxiety agents. It does not include PREANESTHETIC MEDICATION.

Year introduced: 1973(1969)

7.

N,N-di-n-propyl-2-(4-methylphenyl)indol-3-ylglyoxylamide [Supplementary Concept]

Anti-Anxiety Agents; structure in first source

Date introduced: June 21, 2011

8.

wheylin-1 peptide [Supplementary Concept]

Anti-Anxiety Agents; beta-lactoglobulin-derived peptide

Date introduced: October 3, 2014

9.

wheylin-2 peptide [Supplementary Concept]

Anti-Anxiety Agents; beta-lactoglobulin-derived peptide

Date introduced: October 3, 2014

10.

GABA Modulators

Substances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which BENZODIAZEPINES act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which BARBITURATES act to prolong the duration of channel opening; and a site at which some steroids may act. GENERAL ANESTHETICS probably act at least partly by potentiating GABAergic responses, but they are not included here.

Year introduced: 1995

11.

Anxiety Disorders

Persistent and disabling ANXIETY.

Year introduced: 1981

12.

Anxiety

Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

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