MeSH

A plant genus of the family LAMIACEAE best known for the thyme spice added to foods.

Year introduced: 2005

A single, unpaired primary lymphoid organ situated in the MEDIASTINUM, extending superiorly into the neck to the lower edge of the THYROID GLAND and inferiorly to the fourth costal cartilage. It is necessary for normal development of immunologic function early in life. By puberty, it begins to involute and much of the tissue is replaced by fat.

Extracts of the THYMUS GLAND that contain specific factors, peptides, and proteins with specific biological activities.

Year introduced: 1974

Tumors or cancer of the THYMUS GLAND.

Enlargement of the thymus. A condition described in the late 1940's and 1950's as pathological thymic hypertrophy was status thymolymphaticus and was treated with radiotherapy. Unnecessary removal of the thymus was also practiced. It later became apparent that the thymus undergoes normal physiological hypertrophy, reaching a maximum at puberty and involuting thereafter. The concept of status thymolymphaticus has been abandoned. Thymus hyperplasia is present in two thirds of all patients with myasthenia gravis. (From Segen, Dictionary of Modern Medicine, 1992; Cecil Textbook of Medicine, 19th ed, p1486)

Humoral factors secreted by the thymus gland. They participate in the development of the lymphoid system and the maturation of the cellular immune response.

Year introduced: 1977

Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.

Year introduced: 1990 (1973)

Antigens which may directly stimulate B lymphocytes without the cooperation of T lymphocytes.

Year introduced: 1982

A CC-type chemokine with specificity for CCR7 RECEPTORS. It has activity towards DENDRITIC CELLS and T-LYMPHOCYTES.

Year introduced: 2008(1998)

A CC-type chemokine that is found at high levels in the THYMUS and has specificity for CCR4 RECEPTORS. It is synthesized by DENDRITIC CELLS; ENDOTHELIAL CELLS; KERATINOCYTES; and FIBROBLASTS.

Year introduced: 2008

RefSeq NM_005865

Date introduced: March 27, 2003

prss16 is a candidate gene for insulin dependent diabetes mellitus susceptibility; RefSeq NM_019429

Date introduced: March 27, 2003

RefSeq NM_053250

Date introduced: December 14, 2001

a reagent used for routine DNA studies

Date introduced: June 1, 2001

membrane-associated glycoproteins of murine leukemia cells; human thymus leukemia-associated antigen has been recently identified as a thymic isoenzyme of adenosine deaminase 5/28/81

Date introduced: March 11, 1981

A ribonuclease that specifically cleaves the RNA moiety of RNA:DNA hybrids. It has been isolated from a wide variety of prokaryotic and eukaryotic organisms as well as RETROVIRUSES.

Year introduced: 2008, 1992-1993 (1973)

A family of low-molecular weight, non-histone proteins found in chromatin.

Year introduced: 1985

Congenital syndrome characterized by a wide spectrum of characteristics including the absence of the THYMUS and PARATHYROID GLANDS resulting in T-cell immunodeficiency, HYPOCALCEMIA, defects in the outflow tract of the heart, and craniofacial anomalies.

Year introduced: 1991(1977)

Date introduced: November 5, 2012

Epithelial tumors of the thymus. Familial cases are rare and may be associate with a chromosomal translocation involving the RAD51L1 and BMP2 genes. OMIM: 274230

Date introduced: August 25, 2010