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Platelet Aggregation Inhibitors
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
Year introduced: 1988
Platelet Aggregation Inhibitors [Pharmacological Action]
Dual Anti-Platelet Therapy
Treatment with a combination of two types of antiplatelet agents to prevent blood clotting - usually ASPIRIN and another of the PLATELET AGGREGATION INHIBITORS.
Year introduced: 2020
acostatin [Supplementary Concept]
member of the disintegrin family of platelet-aggregation inhibitors found in snake venoms
Date introduced: April 2, 2002
Disintegrins
A family of polypeptides purified from snake venoms, which contain the arginine-glycine-aspartic acid (RGD) sequence. The RGD tripeptide binds to integrin receptors and thus competitively inhibits normal integrin-ligand interactions. Disintegrins thus block adhesive functions and act as platelet aggregation inhibitors.
Year introduced: 1997
Blood Platelets
Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation.
3-(2-oxopropylidene)azetidin-2-one [Supplementary Concept]
derivatives of this compound are platelet aggregation inhibitors; structure given in first source
Date introduced: June 20, 1990
1,4-benzodioxine [Supplementary Concept]
derivatives have potential as platelet aggregation inhibitors, anti-inflammatory, and anti-angiogenic agents
Date introduced: November 29, 2018
2-oxo-benzo(1,4)oxazine [Supplementary Concept]
linked with 2-oxo-2-phenylethylidene in class of non-peptide based platelet aggregation inhibitors
Date introduced: October 18, 2018