Lupus Erythematosus, Systemic
A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
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Subheadings:
Tree Number(s): C17.300.480, C20.111.590
MeSH Unique ID: D008180
Entry Terms:
- Lupus Erythematosus Disseminatus
- Systemic Lupus Erythematosus
- Libman-Sacks Disease
- Disease, Libman-Sacks
- Libman Sacks Disease
See Also: