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Items: 13

1.

Jaundice

A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.

Year introduced: 1965

2.

Jaundice, Obstructive

Jaundice, the condition with yellowish staining of the skin and mucous membranes, that is due to impaired BILE flow in the BILIARY TRACT, such as INTRAHEPATIC CHOLESTASIS, or EXTRAHEPATIC CHOLESTASIS.

Year introduced: 2004

3.

Jaundice, Neonatal

Yellow discoloration of the SKIN; MUCOUS MEMBRANE; and SCLERA in the NEWBORN. It is a sign of NEONATAL HYPERBILIRUBINEMIA. Most cases are transient self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) occurring in the first week of life, but some can be a sign of pathological disorders, particularly LIVER DISEASES.

Year introduced: 1966

4.

Jaundice, Chronic Idiopathic

A benign, autosomally recessive inherited hyperbilirubinemia characterized by the presence of a dark pigment in the centrilobular region of the liver cells. There is a functional defect in biliary excretion of bilirubin, cholephilic dyes, and porphyrins. Affected persons may be asymptomatic or have vague constitutional or gastrointestinal symptoms. The liver may be slightly enlarged, and oral and intravenous cholangiography fails to visualize the biliary tract.

5.

Anemia, hereditary spherocytic hemolytic [Supplementary Concept]

A rare hereditary form of spherocytosis caused by mutations in the ANKYRIN -1 gene (OMIM: 612641). Symptoms include jaundice, excessive fatigue, and delayed puberty.

Date introduced: August 25, 2010

6.

Weil Disease

A severe form of LEPTOSPIROSIS, usually caused by LEPTOSPIRA INTERROGANS SEROVAR ICTEROHAEMORRHAGIAE and occasionally other serovars. It is transmitted to humans by the rat and is characterized by hemorrhagic and renal symptoms with accompanying JAUNDICE.

Year introduced: 2003 (1963)

7.
8.

Gilbert Disease

A benign familial disorder, transmitted as an autosomal dominant trait. It is characterized by low-grade chronic hyperbilirubinemia with considerable daily fluctuations of the bilirubin level.

Year introduced: 2000(1975)

9.
10.

Breastfeeding Jaundice [Supplementary Concept]

Date introduced: November 5, 2012

11.
12.

Hemorrhagic jaundice [Supplementary Concept]

Date introduced: August 25, 2010

13.
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