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HLA-G Antigens
Class I human histocompatibility (HLA) surface antigens encoded by alleles on locus B of the HLA complex. The HLA-G antigens are considered non-classical class I antigens due to their distinct tissue distribution which differs from HLA-A; HLA-B; and HLA-C antigens. Note that several isoforms of HLA-G antigens result from alternative splicing of messenger RNAs produced from the HLA-G*01 allele.
Year introduced: 2012(1990)
G-Protein-Coupled Receptor Kinase 3
A ubiquitously expressed G-protein-coupled receptor kinase subtype that has specificity for the agonist-occupied form of BETA-ADRENERGIC RECEPTORS and a variety of other G-PROTEIN-COUPLED RECEPTORS. Although it is highly homologous to G-PROTEIN-COUPLED RECEPTOR KINASE 2, it is not considered to play an essential role in regulating myocardial contractile response.
Year introduced: 2008(1995)
G(M3) Ganglioside
A ganglioside present in abnormally large amounts in the brain and liver due to a deficient biosynthetic enzyme, G(M3):UDP-N-acetylgalactosaminyltransferase. Deficiency of this enzyme prevents the formation of G(M2) ganglioside from G(M3) ganglioside and is the cause of an anabolic sphingolipidosis.
Year introduced: 1991(1977)
G-Protein-Coupled Receptor Kinases
A family of serine-threonine kinases that are specific for G-PROTEIN-COUPLED RECEPTORS. They are regulatory proteins that play a role in G-protein-coupled receptor densensitization.
Year introduced: 2008
G(M2) Activator Protein
An essential cofactor for the degradation of G(M2)GANGLIOSIDE by lysosomal BETA-N-ACETYLHEXOSAMINIDASES. Genetic mutations resulting in loss of G(M2) activator protein are one of the causes of TAY-SACHS DISEASE, AB VARIANT.
Year introduced: 2005(1983)
ATP Binding Cassette Transporter, Subfamily G, Member 8
ATP-binding cassette transporter, sub-family G protein that functions as a heterodimer with ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY G, MEMBER 5 in the selective transport of DIETARY CHOLESTEROL and PHYTOSTEROLS into and export out of ENTEROCYTES. It also functions in selective sterol excretion by the liver into bile.
Year introduced: 2019 (2017)
ATP Binding Cassette Transporter, Subfamily G, Member 5
ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY G protein that functions as a heterodimer with ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY G, MEMBER 8 in the selective transport of DIETARY CHOLESTEROL and PHYTOSTEROLS into and export out of ENTEROCYTES. It also functions in selective sterol excretion by the liver into bile.
Cyclin G
A cyclin subtype that is found associated with CYCLIN-DEPENDENT KINASE 5; cyclin G associated kinase, and PROTEIN PHOSPHATASE 2.
Year introduced: 2010(1993)
G-Protein-Coupled Receptor Kinase 5
A G-protein-coupled receptor kinase subtype that is primarily expressed in the MYOCARDIUM and may play a role in the regulation of cardiac functions.
Year introduced: 2008(1993)
G-Protein-Coupled Receptor Kinase 4
A G-protein-coupled receptor kinase subtype that is primarily expressed in the TESTES and BRAIN. Variants of this subtype exist due to multiple alternative splicing of its mRNA.
Year introduced: 2008(1994)
G-Protein-Coupled Receptor Kinase 2
A ubiquitously expressed G-protein-coupled receptor kinase subtype that has specificity for the agonist-occupied form of BETA-ADRENERGIC RECEPTORS. It may play an essential role in regulating myocardial contractile response.
G-Box Binding Factors
A family of transcription factors found primarily in PLANTS that bind to the G-box DNA sequence CACGTG or to a consensus sequence CANNTG.
Year introduced: 2006(1992)
G Protein-Coupled Inwardly-Rectifying Potassium Channels
A family of inwardly-rectifying potassium channels that are activated by PERTUSSIS TOXIN sensitive G-PROTEIN-COUPLED RECEPTORS. GIRK potassium channels are primarily activated by the complex of GTP-BINDING PROTEIN BETA SUBUNITS and GTP-BINDING PROTEIN GAMMA SUBUNITS.
Year introduced: 2006(1993)
Clostridium botulinum type G
Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type G. Though it has been isolated from soil, no outbreaks involving this type have been recognized.
Year introduced: 2005
Receptors, G-Protein-Coupled
The largest family of cell surface receptors involved in SIGNAL TRANSDUCTION. They share a common structure and signal through HETEROTRIMERIC G-PROTEINS.
Year introduced: 2004
Peptide Elongation Factor G
Peptide Elongation Factor G catalyzes the translocation of peptidyl-tRNA from the A to the P site of bacterial ribosomes by a process linked to hydrolysis of GTP to GDP.
Year introduced: 2000
Penicillin G Procaine
Semisynthetic antibiotic prepared by combining penicillin G with PROCAINE.
Year introduced: 2010 (1963)
Penicillin G Benzathine
Semisynthetic antibiotic prepared by combining the sodium salt of penicillin G with N,N'-dibenzylethylenediamine.
ATP Binding Cassette Transporter, Subfamily G, Member 2
ATP-binding cassette transporter, sub-family G protein that functions as a high capacity UREA exporter, transporter of STEROLS, and in the absorption and efflux of many drugs. Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE. It functions as a homodimer and is expressed by cells in a variety of organs, as well as by NEOPLASTIC STEM CELLS.
S100 Calcium Binding Protein G
A calbindin protein found in many mammalian tissues, including the UTERUS, PLACENTA, BONE, PITUITARY GLAND, and KIDNEYS. In intestinal ENTEROCYTES it mediates intracellular calcium transport from apical to basolateral membranes via calcium binding at two EF-HAND MOTIFS. Expression is regulated in some tissues by VITAMIN D.
Year introduced: 2014(1979)