alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Year introduced: 1994

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Tree Number(s): D03.383.129.385.025

MeSH Unique ID: D018350

Registry Number: 77521-29-0

Entry Terms:

• alpha Amino 3 hydroxy 5 methyl 4 isoxazolepropionic Acid
• AMPA
• AMPA, (+-)-Isomer
• AMPA, (S)-Isomer
• AMPA, (R)-Isomer
• AMPA, (R)-Isomer, Monohydrobromide
• AMPA, (S)-Isomer, Monohydrobromide

Previous Indexing:

• Ibotenic Acid/analogs and derivatives (1980-1993)

See Also:

• Receptors, AMPA

Pharmacologic Action:

• Excitatory Amino Acid Agonists

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Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, 1-Ring
Azoles
Isoxazoles
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid