Swainsonine

An indolizidine alkaloid from the plant Swainsona canescens that is a potent alpha-mannosidase inhibitor. Swainsonine also exhibits antimetastatic, antiproliferative, and immunomodulatory activity.

Year introduced: 1992

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Tree Number(s): D03.132.830

MeSH Unique ID: D017026

Registry Number: RSY4RK37KQ

Entry Terms:

• Swainsonine, (8 alpha,8a alpha)-Isomer
• Swainsonine, (8 alpha)-Isomer
• Swainsonine, (2 beta,8a alpha)-Isomer
• Swainsonine, (1R-(2 beta,8a alpha))-Isomer
• Swainsonine, (8a alpha)-Isomer

Previous Indexing:

• Alkaloids (1980-1991)

Pharmacologic Action:

• Adjuvants, Immunologic
• Antineoplastic Agents, Phytogenic
• Enzyme Inhibitors

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Alkaloids
Swainsonine