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Methacholine Chloride

A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116)

Year introduced: 1991

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Subheadings:

Tree Number(s): D02.092.877.883.555.500, D02.675.276.534.500

MeSH Unique ID: D016210

Registry Number: 0W5ETF9M2K

Entry Terms:

  • Chloride, Methacholine
  • Acetyl-2-methylcholine Chloride
  • Acetyl 2 methylcholine Chloride
  • Acetyl-beta-methacholine Chloride
  • Acetyl beta methacholine Chloride
  • 2-(Acetyloxy)-N,N,N-trimethyl-1-propanaminium Chloride
  • Mecholine
  • Mecholyl
  • Acetyl-beta-methylcholine
  • Acetyl beta methylcholine
  • Methacholine
  • Provocholine
  • Provokit

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