Valinomycin

A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring. (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies.

Year introduced: 1973(1971)

PubMed search builder options

Subheadings:

Restrict to MeSH Major Topic.

Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): D04.345.566.297.500, D12.644.641.297.500

MeSH Unique ID: D014634

Registry Number: 2001-95-8

Previous Indexing:

• Antibiotics (1966-1970)

Pharmacologic Action:

• Anti-Bacterial Agents
• Ionophores

All MeSH Categories
Chemicals and Drugs Category
Polycyclic Compounds
Macrocyclic Compounds
Peptides, Cyclic
Depsipeptides
Valinomycin

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Peptides
Peptides, Cyclic
Depsipeptides
Valinomycin