Pimozide

A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to HALOPERIDOL for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403)

Year introduced: 1973

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Tree Number(s): D03.633.100.103.732

MeSH Unique ID: D010868

Registry Number: 1HIZ4DL86F

Entry Terms:

• R-6238
• R6238
• Antalon
• Orap
• Orap forte

Previous Indexing:

• Benzimidazoles (1966-1972)
• Tranquilizing Agents (1966-1972)

Pharmacologic Action:

• Antipsychotic Agents
• Dopamine Antagonists
• Anti-Dyskinesia Agents

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, Fused-Ring
Heterocyclic Compounds, 2-Ring
Benzimidazoles
Pimozide