Dextromethorphan
Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.
Year introduced: 1991(1972)
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Tree Number(s): D03.132.577.249.200, D03.605.497.212, D03.633.400.686.212, D04.615.723.795.200
MeSH Unique ID: D003915
Registry Number: 7355X3ROTS
Entry Terms:
- d-Methorphan
- Racemethorphan
- Dextromethorphan Hydrobromide
- Hydrobromide, Dextromethorphan
- Dextromethorphan Hydrochloride
- Hydrochloride, Dextromethorphan
- Dextromethorphan, (+-)-Isomer
- Dextromethorphan Hydrobromide, (+-)-Isomer
- Delsym
- Dextromethorphan Hydrobromide, Monohydrate
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