Mirtazapine
A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.
Year introduced: 2019 (1982)
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Subheadings:
Tree Number(s): D03.633.300.240.588
MeSH Unique ID: D000078785
Registry Number: A051Q2099Q
Entry Terms:
- 6-Azamianserin
- 6 Azamianserin
- Remeron
- Zispin
- Norset
- Remergil
- ORG 3770
- ORG-3770
- ORG3770
- Rexer
- Esmirtazapine
- (S)-Mirtazapine
- Org 50081
- (N-Methyl-11C)mirtazapine
Pharmacologic Action: