Pegloticase [Supplementary Concept]
uricase covalently attached to polyethylene glycol, modifying 71% of amino groups & retaining 11% of activity without eliciting antibody response in mice or man; used for lowering serum uric acid
Date introduced: September 11, 1981
MeSH Unique ID: C031545
Registry Number: R581OT55EA
Heading Mapped to:
Entry Terms:
- PEG-uricase
- methoxypolyethylene glycol uricase
- polyethylene glycol-uricase
- Puricase
- Krystexxa