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Amikacin
A broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and oto-toxic like the other aminoglycoside antibiotics.
Year introduced: 1987(1975)
Kanamycin Kinase
A class of enzymes that inactivate aminocyclitol-aminoglycoside antibiotics (AMINOGLYCOSIDES) by regiospecific PHOSPHORYLATION of the 3' and/or 5' hydroxyl.
Year introduced: 1998
aminoglycoside N(6')-acetyltransferase [Supplementary Concept]
the antibiotics kanamycin, gentamicin, tobramycin, and neomycin can act as an acceptor; has to be 6'-acetyltransferase
Date introduced: August 12, 1988