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1.

Adenine

A purine base and a fundamental unit of ADENINE NUCLEOTIDES.

2.

Adenine Nucleotide Translocator 3

A subtype of mitochondrial ADP, ATP translocase found primarily in the LIVER.

Year introduced: 2003

3.

Adenine Nucleotide Translocator 2

A subtype of mitochondrial ADP, ATP translocase found primarily in FIBROBLASTS.

Year introduced: 2003

4.

Adenine Nucleotide Translocator 1

A subtype of mitochondrial ADP, ATP translocase found primarily in heart muscle (MYOCARDIUM) and skeletal muscle (MUSCLE, SKELETAL).

Year introduced: 2003

5.

Site-Specific DNA-Methyltransferase (Adenine-Specific)

An enzyme responsible for producing a species-characteristic methylation pattern on adenine residues in a specific short base sequence in the host cell DNA. The enzyme catalyzes the methylation of DNA adenine in the presence of S-adenosyl-L-methionine to form DNA containing 6-methylaminopurine and S-adenosyl-L-homocysteine. EC 2.1.1.72.

Year introduced: 1998(1989)

6.

Flavin-Adenine Dinucleotide

A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)

Year introduced: 2002(1963)

7.

Adenine Phosphoribosyltransferase

An enzyme catalyzing the formation of AMP from adenine and phosphoribosylpyrophosphate. It can act as a salvage enzyme for recycling of adenine into nucleic acids. EC 2.4.2.7.

Year introduced: 1991(1975)

8.
9.

9-(2-hydroxy-3-nonyl)adenine [Supplementary Concept]

specific inhibitor of adenosine deaminase

Date introduced: January 1, 1975

10.
11.

NAD

A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)

12.

9-(S)-(3-hydroxy-2-(phosphonomethoxy)propyl)adenine [Supplementary Concept]

broad-spectrum anti-DNA virus agent

Date introduced: November 5, 1986

13.
14.

Tenofovir

An adenine analog REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIVIRAL AGENTS, due to the emergence of ANTIVIRAL DRUG RESISTANCE when it is used alone.

Year introduced: 2016 (2001)

15.

NADP

Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)

16.

SLC25A31 protein, human [Supplementary Concept]

RefSeq NM_031291

Date introduced: April 12, 2007

17.

9-(bis(hydroxymethyl)thietan-1'-yl)adenine [Supplementary Concept]

structure in first source

Date introduced: June 23, 2000

18.

1,3-dideaza-9-(2-hydroxy-3-nonyl)adenine [Supplementary Concept]

RN & structure given in first source; RN given refers to parent cpd

Date introduced: March 15, 1988

19.

7-deaza-9-(2-hydroxy-3-nonyl)adenine [Supplementary Concept]

RN & structure given in first source; RN given refers to parent cpd

Date introduced: March 15, 1988

20.

9-(2',3'-dihydroxycyclopent-4'-enyl)adenine [Supplementary Concept]

structure given in first source; S-adenosyl homocysteine hydrolase antagonist

Date introduced: March 9, 1988

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