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  • The following terms were not found in MeSH: Cyclopentanediamine, 3-Cyclopentanediamine.
1.

3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer

A non-peptide, kappa-opioid receptor agonist which has also been found to stimulate the release of adrenocorticotropin (ADRENOCORTICOTROPIC HORMONE) via the release of hypothalamic arginine vasopressin (ARGININE VASOPRESSIN) and CORTICOTROPIN-RELEASING HORMONE. (From J Pharmacol Exp Ther 1997;280(1):416-21)

Year introduced: 2002(1998)

2.

Catechol 2,3-Dioxygenase

Catalyzes the oxidation of catechol to 2-hydroxymuconate semialdehyde in the carbazole and BENZOATE degradation via HYDROXYLATION pathways. It also catalyzes the conversion of 3-methylcatechol to cis, cis-2-hydroxy-6-oxohept-2,4-dienoate in the TOLUENE and XYLENE degradation pathway. This enzyme was formerly characterized as EC 1.13.1.2.

Year introduced: 2006(1981)

3.

Protocatechuate-3,4-Dioxygenase

An enzyme that catalyzes the oxidation of protocatechuate to 3-carboxy-cis-cis-muconate in the presence of molecular oxygen. It contains ferric ion. EC 1.13.11.3.

Year introduced: 1991(1975)

4.

1-amino-1,3-dicarboxycyclopentane [Supplementary Concept]

RN given refers to (cis)-isomer

Date introduced: December 13, 1982

5.

3-methylfentanyl [Supplementary Concept]

RN given refers to parent cpd without isomeric designation

Date introduced: July 30, 1981

6.

1,3-dimethyl-1,2,3,4-tetrahydroisoquinoline [Supplementary Concept]

RN given refers to parent cpd

Date introduced: September 13, 1990

7.

3-aminocyclopentane-1-carboxylic acid [Supplementary Concept]

structure given in first source; a selective GABA-A agonist; a cyclopentane analog of GABA; RN given for (trans)-isomer

Date introduced: August 4, 1992

8.

platinum(II) 1,2-diaminocyclohexane malonate [Supplementary Concept]

RN given refers to (SP-4-2-(trans))-isomer

Date introduced: January 1, 1976

9.

dichloro-1-hydroxy-3,4-diaminocyclohexane platinum complex [Supplementary Concept]

structure given in first source; RN given refers to the (1alpha,3beta,4beta)-isomer

Date introduced: February 1, 1989

10.

3-phenyl-3-(N-piperidinyl)bicyclo(3.1.0)hexane [Supplementary Concept]

RN & structure given in first source; RN given refers to (cis)-isomer; RN for cpd without isomeric designation not available 9/88

Date introduced: September 1, 1988

11.

Oxaliplatin

An organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane, and with an oxalate ligand which is displaced to yield active oxaliplatin derivatives. These derivatives form inter- and intra-strand DNA crosslinks that inhibit DNA replication and transcription. Oxaliplatin is an antineoplastic agent that is often administered with FLUOROURACIL and FOLINIC ACID in the treatment of metastatic COLORECTAL NEOPLASMS.

Year introduced: 2019 (1981)

12.

1-phenyl-3-(3-methoxy-2-propoxy-5-(4-(3,4,5-trimethoxyphenyl)-1,3-dithiolane-2-yl)phenyl)thiourea [Supplementary Concept]

increases production of nitric oxide; ZX-4 and ZX-5 are the (cis)- and (trans)-isomers, respectively; structure in first source

Date introduced: January 23, 2004

13.

Catechin

An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.

Year introduced: 1987(1977)

14.

1,1-dichloro-2,3-diphenyl-2-(4-methoxyphenyl)cyclopropane [Supplementary Concept]

may be highly effective in treatment of estrogen-dependent breast cancer; structure given in first source; RN given refers to the (cis)-isomer

Date introduced: August 1, 1992

15.

dichloro-1,2-diaminocyclohexane platinum complex [Supplementary Concept]

RN given refers to (SP-4-2)-isomer

Date introduced: January 1, 1977

16.

abrocitinib [Supplementary Concept]

Janus kinase 1 inhibitor

Date introduced: September 23, 2019

17.

3-iododizocilpine [Supplementary Concept]

RN given for (+-)-isomer,125I-labeled cpd; structure in first source

Date introduced: June 6, 1997

18.

dicarbine [Supplementary Concept]

minor descriptor (77-84); on-line & Index Medicus search CARBOLINES (77-84); RN given refers to parent cpd without isomeric designation

Date introduced: August 10, 1984

19.

2,3,3a,4,5,9b-hexahydro-1-methyl-1H-pyrrolo(3,2-h)isoquinoline [Supplementary Concept]

a bridged nicotine analog; structure given in first source; RN given refers to (cis-(+-))-isomer

Date introduced: December 9, 1993

20.
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