Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
TAK-070 [Supplementary Concept]
a noncompetitive BACE1/beta-site APP cleaving enzyme 1 inhibitor; structure in first source
Date introduced: September 2, 2010
stearylamine [Supplementary Concept]
RN given refers to parent cpd
Date introduced: January 1, 1969
oleylamine [Supplementary Concept]
promotes fusion of mouse A(9) fibroblasts; RN given refers to parent cpd with unspecified isomeric designation; structure
Date introduced: January 1, 1974
Chlordiazepoxide
An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
cariprazine [Supplementary Concept]
Structure in first source
Date introduced: December 1, 2008
1,3-dimethyl-7-(2-hydroxy-3-(1-piperidino)propyl)-8-phenylxanthineamine [Supplementary Concept]
has membranotropic activity
Date introduced: January 26, 2013
rasagiline [Supplementary Concept]
TVP-1022 is the (S)-isomer and a cardioprotective agent; monoamine oxidase type-B inhibitor that is not metabolized to amphetamine derivatives; can lead to fatal hypertensive crisis in patients who consume tyramine-rich foods
Date introduced: November 22, 1981
3,3'-(methylimino)di-1-propanoldimethanesulfonate [Supplementary Concept]
NSC 84641 is the salt form; RN given refers to parent cpd; structure
N-(4-pyridinyl)-1H-indol-1-amine [Supplementary Concept]
a metabolite of besiperdine (HP 749); structure given in first source; P7480 is HCl
Date introduced: November 8, 1995
besipirdine [Supplementary Concept]
structure given in first source; a non-receptor-dependent cholinomimetic agent with noradrenergic activity with potential use for treating Alzheimer's disease
Date introduced: July 1, 1992
BRD4780 [Supplementary Concept]
Date introduced: April 29, 2021
(2-(4-tert-butyl-1-(3,4-dichloro-benzyl)-cyclohexyloxy)-ethyl)-dimethyl-amine hydrochloride [Supplementary Concept]
structure in first source
Date introduced: August 17, 2012
irampanel [Supplementary Concept]
Date introduced: June 14, 1999
benzyl-(2-chloroethyl)-(2-(2-methoxyphenoxy)-1-methylethyl)amine [Supplementary Concept]
Date introduced: December 15, 1997
S 28828 [Supplementary Concept]
an analog of imiquimod; structure given in first source
Date introduced: May 28, 1997
9-tetradecenylamine [Supplementary Concept]
isolated from the ant Monomorium floricola; structure given in first source; RN given refers to cis-isomer
Date introduced: January 19, 1997
nerispirdine [Supplementary Concept]
inhibits batrachotoxin binding to voltage-dependent sodium channels; HP-184 is the HCl salt
Date introduced: October 14, 1996
thiambutene [Supplementary Concept]
non-opioid; used mainly in veterinary medicine; minor descriptor (76-84); on-line & Index Medicus search THIOPHENES (76-84); RN given refers to parent cpd
Date introduced: August 14, 1984
fencamfamine [Supplementary Concept]
Date introduced: January 1, 1979
cyclindole [Supplementary Concept]
RN given refers to parent cpd; structure
Date introduced: January 1, 1972