Myotonin-Protein Kinase
Serine/threonine protein kinase responsible for various SKELETAL MUSCLE functions; HEART CONDUCTION SYSTEM activity; calcium HOMEOSTASIS; calcium uptake by SARCOPLASMIC RETICULUM and SYNAPTIC PLASTICITY. It is encoded by the DMPK gene and its abnormal EXPANDED TRINUCLEOTIDE REPEAT of CTG in the 3'-UTR is associated with MYOTONIC DYSTROPHY 1.
Year introduced: 2015
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Subheadings:
Tree Number(s): D08.811.913.696.620.682.700.576, D12.776.476.563.576
MeSH Unique ID: D065636
Registry Number: EC 2.7.11.1
Entry Terms:
- Kinase, Myotonin-Protein
- Myotonin Protein Kinase
- MDGP Protein
- Protein, MDGP
- Myotonic Dystrophy Protein Kinase
- DM1PK Protein
- Protein, DM1PK
- MDPK Protein
- Protein, MDPK
- DM Protein Kinase
- Kinase, DM Protein
- Protein Kinase, DM
- DMPK Protein
- Protein, DMPK
- DM-Kinase
- DM Kinase
See Also: