Lopinavir

An HIV protease inhibitor used in a fixed-dose combination with RITONAVIR. It is also an inhibitor of CYTOCHROME P-450 CYP3A.

Year introduced: 2012

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Tree Number(s): D03.383.742.698.553

MeSH Unique ID: D061466

Registry Number: 2494G1JF75

Entry Terms:

• N-(4-(((2,6-dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pydrimidineacetamide
• ABT 378
• ABT-378
• ABT378
• A-157378.0
• A 157378.0
• A157378.0

Pharmacologic Action:

• HIV Protease Inhibitors
• Cytochrome P-450 CYP3A Inhibitors

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, 1-Ring
Pyrimidines
Pyrimidinones
Lopinavir