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Hyper-IgM Immunodeficiency Syndrome

A rare inherited immunodeficiency syndrome characterized by normal or elevated serum IMMUNOGLOBULIN M levels with absence of IMMUNOGLOBULIN G; IMMUNOGLOBULIN A; and IMMUNOGLOBULIN E. It results in a profound susceptibility to BACTERIAL INFECTIONS and an increased susceptibility to OPPORTUNISTIC INFECTIONS. Several subtypes of hyper-IgM immunodeficiency syndrome exist depending upon the location of genetic mutation.

Year introduced: 2007

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Tree Number(s): C15.378.147.333.249, C16.320.413, C16.320.798.625, C20.673.430.250, C20.673.795.625

MeSH Unique ID: D053306

Entry Terms:

  • Hyper IgM Immunodeficiency Syndrome
  • Hyper-IgM Immunodeficiency Syndromes
  • Immunodeficiency Syndrome, Hyper-IgM
  • Immunodeficiency Syndromes, Hyper-IgM
  • Syndrome, Hyper-IgM Immunodeficiency
  • Syndromes, Hyper-IgM Immunodeficiency
  • Hyper-IgM Syndrome
  • Hyper IgM Syndrome
  • Hyper-IgM Syndromes
  • Immunodeficiency with Hyper-IgM Syndrome
  • Immunodeficiency with Hyper IgM Syndrome
  • Hyper-IgM Immunodeficiency Syndrome, Type 2
  • Hyper IgM Immunodeficiency Syndrome, Type 2
  • Hyper-IgM Syndrome 2
  • Hyper IgM Syndrome 2
  • HIGM2 Syndrome
  • HIGM2 Syndromes
  • Hyper-IgM Immunodeficiency Syndrome Type 2
  • Hyper IgM Immunodeficiency Syndrome Type 2
  • Immunodeficiency with Hyper-IgM, Type 2
  • Immunodeficiency with Hyper IgM, Type 2
  • Hyper-IgM Immunodeficiency Syndrome, Type 3
  • Hyper IgM Immunodeficiency Syndrome, Type 3
  • HIGM3 Syndrome
  • HIGM3 Syndromes
  • Hyper-IgM Syndrome 3
  • Hyper IgM Syndrome 3
  • Hyper-IgM Immunodeficiency Syndrome Type 3
  • Hyper IgM Immunodeficiency Syndrome Type 3
  • Immunodeficiency with Hyper-IgM, Type 3
  • Immunodeficiency with Hyper IgM, Type 3
  • Hyper-IgM Immunodeficiency Syndrome, Type 5
  • Hyper IgM Immunodeficiency Syndrome, Type 5
  • HIGM5 Syndrome
  • HIGM5 Syndromes
  • Hyper-IgM Syndrome 5
  • Hyper IgM Syndrome 5
  • Hyper-IgM Syndrome 5s
  • Hyper-IgM Immunodeficiency Syndrome Type 5
  • Hyper IgM Immunodeficiency Syndrome Type 5
  • Immunodeficiency with Hyper-IgM, Type 5
  • Immunodeficiency with Hyper IgM, Type 5

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